Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | RECQL | P46063 | 3/20 | 0.57 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TTR | P02766 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996324 | 0.85 | FTO (0.68) | ALDH1A1MAPTTSHRTDP1MEN1 | |
| SCHEMBL2148493 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MAPTTSHRTDP1MEN1 | |
| SCHEMBL23723959 | 0.77 | FTO (0.73) | ALDH1A1MAPTTSHRTDP1MEN1 | |
| SCHEMBL30695844 | 0.76 | MAOA (0.86) | ALDH1A1MAPTTSHRTDP1MEN1 | |
| SCHEMBL3198327 | 0.76 | MAOA (0.86) | ALDH1A1MAPTTSHRTDP1MEN1 | |
| SCHEMBL16224286 | 0.75 | MAPT (0.68) | ALDH1A1MAPTTSHRTDP1MEN1 | |
| SCHEMBL430100 | 0.74 | TTR (0.91) | ALDH1A1MAPTTSHRTDP1MEN1 | |
| Anthrarufin SCHEMBL29874705 | 0.74 | MAOA (1.00) | ALDH1A1MAPTTSHRTDP1MEN1 | |
| Anthrarufin SCHEMBL29363946 | 0.74 | MAOA (1.00) | ALDH1A1MAPTTSHRTDP1MEN1 | |
| Anthrarufin SCHEMBL187843 | 0.74 | MAOA (1.00) | ALDH1A1MAPTTSHRTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588797-B1 | N- 4,5-DIHYDROXY- AND 4,5,8-TRIHYDROXY-9,10-DIHYDRO-9,10-DIOXO-2-ANTHRACENE-YL]CARBONYL]AMINO ACIDS USEFUL IN THE THERAPY OF OSTEOARTICULAR AFFECTIONS | GENTILI IST SPA (IT) | 1996-02-21 | — | — | EP | disclosed |
| US-5451606-A | Anthraquinone compounds useful to treat osteoarticular conditions, pharmaceutical compositions and method of treatment | ISTITUTO GENTILI S.P.A. (IT) | 1995-09-19 | — | — | US | disclosed |