Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.35 |
| ▸ | KIT | P10721 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | DGKA | P23743 | 2/20 | 0.32 |
| ▸ | DGKZ | Q13574 | 2/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963694 | 0.90 | TRPV1 (0.37) | KIT | |
| SCHEMBL8963753 | 0.70 | ADRA2A (0.43) | MAPTSMOPIN1 | |
| SCHEMBL8963661 | 0.68 | CYP3A4 (0.49) | LMNA | |
| SCHEMBL8963706 | 0.66 | LIMK2 (0.39) | SLC6A9DGKADGKZ | |
| SCHEMBL8964029 | 0.66 | DRD4 (0.44) | TP53MAPTTSHR | |
| SCHEMBL8963977 | 0.66 | NPY5R (0.35) | MAPTDGAT1 | |
| SCHEMBL8963675 | 0.64 | TACR1 (0.36) | PIN1 | |
| Hydrochloric Acid SCHEMBL8963757 | 0.63 | OPRM1 (0.43) | MAPTSLC6A9LMNAPIN1 | |
| Hydrochloric Acid SCHEMBL8963766 | 0.61 | OPRM1 (0.42) | MAPTSLC6A9LMNAPIN1 | |
| SCHEMBL8964126 | 0.60 | CTSS (0.52) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |