Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2916977 | 1.00 | HRH2 (0.47) | HRH2HRH1HSD17B3HRH3TBXAS1 | |
| SCHEMBL10622903 | 1.00 | HRH2 (0.47) | HRH2HRH1HSD17B3HRH3TBXAS1 | |
| SCHEMBL2916182 | 1.00 | HRH2 (0.47) | HRH2HRH1HSD17B3HRH3TBXAS1 | |
| SCHEMBL4186059 | 1.00 | HRH2 (0.47) | HRH2HRH1HSD17B3HRH3TBXAS1 | |
| SCHEMBL8963848 | 0.91 | TBXAS1 (0.49) | HRH2HRH1HRH3TBXAS1ALDH1A1 | |
| SCHEMBL10625908 | 0.91 | SLC6A5 (0.54) | SLC6A5FFAR1ALDH1A1 | |
| SCHEMBL10623012 | 0.89 | ALDH1A1 (0.52) | SLC6A5FFAR1ALDH1A1 | |
| SCHEMBL6665692 | 0.86 | AOC1 (0.43) | HRH2HRH1HRH3ALDH1A1MAPT | |
| SCHEMBL5217908 | 0.78 | — | — | |
| SCHEMBL5269768 | 0.75 | TSHR (0.50) | HRH3TBXAS1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797124-B1 | COVALENT GRAFTING OF HYDROPHOBIC SUBSTANCES ON COLLAGEN | BIOM UP (FR) | 2010-09-01 | — | — | EP | disclosed |
| US-20070260299-A1 | Covalent Grafting of Hydrophobic Substances on Collagen | INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (FR) | 2007-11-08 | — | — | US | disclosed |
| EP-1797124-A1 | COVALENT GRAFTING OF HYDROPHOBIC SUBSTANCES ON COLLAGEN | INSA (Institut National des Sciences Appliqées) (FR) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006037770-A1 | COVALENT GRAFTING OF HYDROPHOBIC SUBSTANCES ON COLLAGEN | INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (FR) | 2006-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070260299-A1 | Covalent Grafting of Hydrophobic Substances on Collagen | COL14A1, COL1A1, COL2A1 | HRH2 447/4885HRH1 397/4885HSD17B3 3494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.