SCHEMBL2272071

SCHEMBL2272071

Cl[SiH2]CCCc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 5/20 0.48
MAOA P21397 1/20 0.48
MAOB P27338 2/20 0.46
HTR2A P28223 1/20 0.46
IDO1 P14902 1/20 0.45
HDAC3 O15379 1/20 0.45
MAPK1 P28482 1/20 0.45
ADRA1A P35348 1/20 0.45
HDAC4 P56524 1/20 0.45
SLC6A3 Q01959 1/20 0.45
HDAC1 Q13547 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC10 Q969S8 1/20 0.45
HDAC11 Q96DB2 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
HDAC9 Q9UKV0 1/20 0.45
HDAC5 Q9UQL6 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2684480 0.85 ALDH1A1 (0.48) SIGMAR1MAOAMAOBHTR2AIDO1
Chloromethane SCHEMBL29048090 0.81 ALDH1A1 (0.44) MAOAMAOBHTR2ASMN1; SMN2ALDH1A1
SCHEMBL1882499 0.80 MAOA (0.58) SIGMAR1MAOAMAOBHTR2AIDO1
SCHEMBL28751041 0.79 CA1 (0.34) MAOBHTR2AALOX15
SCHEMBL11457819 0.76 ALDH1A1 (0.55) SIGMAR1MAOAMAOBHTR2ASMN1; SMN2
SCHEMBL8766061 0.76 HDAC3 (0.50) SIGMAR1MAOAMAOBHTR2AIDO1
SCHEMBL8964010 0.76 L3MBTL1 (0.48) SIGMAR1MAOAMAOBHTR2AIDO1
SCHEMBL8766068 0.76 HDAC3 (0.50) SIGMAR1MAOAMAOBHTR2AIDO1
SCHEMBL451456 0.76 MAOA (0.74) SIGMAR1MAOAMAOBHTR2AIDO1
SCHEMBL54347 0.76 HTR2A (0.70) SIGMAR1MAOAMAOBHTR2AIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115748258-A Novel environment-friendly antibacterial deodorizing finishing agent and preparation method thereof 广东湛丰精细化工有限公司 2023-03-07 CN claimed
CN-115748258-A Novel environment-friendly antibacterial deodorizing finishing agent and preparation method thereof 广东湛丰精细化工有限公司 2023-03-07 CN disclosed
CN-108336329-B Positive electrode active material and battery 松下知识产权经营株式会社 2022-08-19 CN disclosed
CN-108336329-A Positive active material and battery 松下知识产权经营株式会社 2018-07-27 CN disclosed
CN-102203226-B Lubricant and magnetic disk MORESCO CORP. (JP) 2015-11-25 CN disclosed
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
CN-102203226-A Lubricant and magnetic disk MORESCO CORP 2011-09-28 CN disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed