Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963552 | 0.87 | SLC6A4 (0.42) | SLC6A4SLC6A2CYP3A4CYP2D6MEN1 | |
| Hydrochloric Acid SCHEMBL8963748 | 0.85 | SLC6A4 (0.38) | SLC6A4SLC6A2CYP3A4CYP2D6MEN1 | |
| Hydrochloric Acid SCHEMBL8963761 | 0.80 | MAPT (0.38) | CYP2D6KMT2ATSHROPRD1OPRM1 | |
| SCHEMBL8963690 | 0.78 | PRMT5 (0.37) | SLC6A4SLC6A2MEN1KMT2AOPRD1 | |
| SCHEMBL8963956 | 0.77 | SLC6A4 (0.40) | SLC6A4SLC6A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL8963459 | 0.76 | PRMT5 (0.36) | SLC6A4SLC6A2MEN1KMT2AOPRD1 | |
| Hydrochloric Acid SCHEMBL8963592 | 0.76 | MAPT (0.39) | CYP2D6KMT2ATSHROPRD1OPRM1 | |
| SCHEMBL8969991 | 0.75 | OPRD1 (0.37) | SLC6A4SLC6A2MEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL8963634 | 0.75 | SLC6A4 (0.39) | SLC6A4SLC6A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL8963762 | 0.75 | HTR7 (0.44) | SLC6A4SLC6A2CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |