Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.32 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963690 | 0.94 | PRMT5 (0.37) | PRMT5SLC6A4SLC6A2MEN1KMT2A | |
| SCHEMBL8963580 | 0.84 | PRMT5 (0.40) | PRMT5SLC6A4SLC6A2MEN1KMT2A | |
| SCHEMBL8963817 | 0.83 | PRMT5 (0.42) | PRMT5SLC6A4SLC6A2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8963783 | 0.83 | PRMT5 (0.40) | PRMT5SLC6A4SLC6A2MEN1KMT2A | |
| SCHEMBL8963826 | 0.80 | PRMT5 (0.40) | PRMT5SLC6A4SLC6A2MEN1KMT2A | |
| SCHEMBL8963679 | 0.78 | MEN1 (0.42) | PRMT5SLC6A4SLC6A2MEN1KMT2A | |
| SCHEMBL8964088 | 0.78 | OPRD1 (0.37) | PRMT5MEN1KMT2AOPRD1OPRM1 | |
| SCHEMBL8964111 | 0.76 | SLC6A4 (0.41) | SLC6A4SLC6A2MEN1KMT2AOPRD1 | |
| SCHEMBL8963650 | 0.76 | CHEK2 (0.40) | PRMT5SLC6A4SLC6A2MEN1KMT2A | |
| SCHEMBL8963637 | 0.76 | MAPK13 (0.37) | PRMT5SLC6A4SLC6A2HRH3OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |