Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963956 | 0.89 | SLC6A4 (0.40) | SLC6A4SLC6A2MEN1KMT2ACYP1A2 | |
| SCHEMBL8963679 | 0.87 | MEN1 (0.42) | SLC6A4SLC6A2MEN1KMT2ATSHR | |
| SCHEMBL8963762 | 0.87 | HTR7 (0.44) | SLC6A4SLC6A2MEN1KMT2ACYP2D6 | |
| SCHEMBL8964111 | 0.87 | SLC6A4 (0.41) | SLC6A4SLC6A2MEN1KMT2ACYP1A2 | |
| SCHEMBL8969991 | 0.87 | OPRD1 (0.37) | SLC6A4SLC6A2MEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL8963634 | 0.85 | SLC6A4 (0.39) | SLC6A4SLC6A2MEN1KMT2ACYP1A2 | |
| SCHEMBL8963580 | 0.84 | PRMT5 (0.40) | SLC6A4SLC6A2MEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL8963783 | 0.83 | PRMT5 (0.40) | SLC6A4SLC6A2MEN1KMT2ACYP1A2 | |
| SCHEMBL8963699 | 0.83 | MEN1 (0.45) | SLC6A4SLC6A2MEN1KMT2ATSHR | |
| SCHEMBL8963650 | 0.82 | CHEK2 (0.40) | SLC6A4SLC6A2MEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |