Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963552 | 0.87 | SLC6A4 (0.42) | OPRD1MEN1KMT2ASLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL8964008 | 0.86 | OPRD1 (0.36) | OPRD1MEN1KMT2ASLC6A4SLC6A2 | |
| SCHEMBL8963956 | 0.85 | SLC6A4 (0.40) | MEN1KMT2ASLC6A4SLC6A2CYP1A2 | |
| SCHEMBL8963679 | 0.83 | MEN1 (0.42) | OPRD1MEN1KMT2ASLC6A4SLC6A2 | |
| SCHEMBL8963762 | 0.83 | HTR7 (0.44) | MEN1KMT2ASLC6A4SLC6A2TACR1 | |
| SCHEMBL8963467 | 0.83 | OPRD1 (0.41) | OPRD1MEN1KMT2ASLC6A4SLC6A2 | |
| SCHEMBL8963715 | 0.82 | MEN1 (0.41) | OPRD1MEN1KMT2ASLC6A4SLC6A2 | |
| SCHEMBL8964174 | 0.81 | TACR1 (0.38) | OPRD1MEN1KMT2ASLC6A4SLC6A2 | |
| SCHEMBL8963580 | 0.81 | PRMT5 (0.40) | OPRD1MEN1KMT2ASLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL8963601 | 0.80 | CYP2D6 (0.36) | OPRD1MEN1KMT2ATSHRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |