Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 11/20 | 0.36 |
| ▸ | PPARA | Q07869 | 8/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11449606 | 0.84 | ALDH1A1 (0.37) | MTNR1AMTNR1BCYP1A2PPARGPPARA | |
| SCHEMBL10463887 | 0.84 | ADCY6 (0.35) | MTNR1AMTNR1BGAACYP2C19CHRM1 | |
| SCHEMBL10362695 | 0.78 | KDM4E (0.33) | KDM4E | |
| SCHEMBL8589695 | 0.75 | MTNR1A (0.37) | MTNR1AMTNR1BCYP1A2GAACYP2C9 | |
| SCHEMBL11063759 | 0.73 | KDM4E (0.44) | MTNR1AMTNR1BCYP1A2GAACYP2C9 | |
| SCHEMBL28863032 | 0.73 | L3MBTL1 (0.40) | CYP1A2PKMCYP2C19CHRM1ALDH1A1 | |
| SCHEMBL13324879 | 0.71 | KDM4E (0.55) | GAAPPARGPPARACHRM1KDM4E | |
| SCHEMBL21881586 | 0.71 | KDM4E (0.55) | GAAPPARGPPARACHRM1KDM4E | |
| SCHEMBL16145065 | 0.71 | SRC (0.33) | — | |
| SCHEMBL660871 | 0.71 | KDM4E (0.55) | GAAPPARGPPARACHRM1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536736-A | CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |