Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967205 | 1.00 | CHRNB2 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL8967740 | 0.84 | TK1 (0.42) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL8967745 | 0.84 | TK1 (0.42) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL16724553 | 0.77 | CHRNB2 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL12648155 | 0.73 | CHRNB2 (0.45) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL17533507 | 0.73 | CHRNB2 (0.45) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL12647805 | 0.73 | CHRNB2 (0.45) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL443828 | 0.71 | CHRNB2 (0.53) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL443829 | 0.71 | ALDH1A1 (0.55) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL11161091 | 0.69 | SLC18A3 (0.43) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204474-A | Providing polymers with oxidation, heat and radiation resistances | CIBA-GEIGY CORPORATION (US) | 1993-04-20 | — | — | US | claimed |
| JP-5194388-A | — | — | None | — | — | JP | disclosed |
| EP-0521820-B1 | 2,6-Diarylpiperidin-1-yl substituted 2-butene stabilizers | CIBA GEIGY AG (CH) | 1996-02-07 | — | — | EP | disclosed |
| US-5290940-A | 2,6-diarylpiperidin-1-yl substituted 2-butene stabilizers | CIBA-GEIGY CORPORATION (US) | 1994-03-01 | — | — | US | disclosed |
| JP-H05194388-A | 2-6-DIARYLPIPERIDIN-1-YL SUBSTITUTED 2-BUTENE STABILIZER | CIBA GEIGY AG | 1993-08-03 | — | — | JP | disclosed |
| US-5204474-A | Providing polymers with oxidation, heat and radiation resistances | CIBA-GEIGY CORPORATION (US) | 1993-04-20 | — | — | US | disclosed |
| EP-0521820-A1 | 2,6-Diarylpiperidin-1-yl substituted 2-butene stabilizers | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | disclosed |