Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | AGER | Q15109 | 3/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967740 | 1.00 | TK1 (0.42) | TK1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL8967205 | 0.84 | CHRNB2 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL8967210 | 0.84 | CHRNB2 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL9016986 | 0.73 | TK1 (0.49) | TK1G6PC1OPRM1OPRD1OPRK1 | |
| SCHEMBL8421536 | 0.73 | TK1 (0.49) | TK1G6PC1OPRM1OPRD1OPRK1 | |
| SCHEMBL16724553 | 0.71 | CHRNB2 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL9016990 | 0.70 | OPRM1 (0.51) | G6PC1OPRM1OPRD1OPRK1 | |
| SCHEMBL9016988 | 0.70 | OPRM1 (0.51) | G6PC1OPRM1OPRD1OPRK1 | |
| SCHEMBL9016964 | 0.68 | OPRM1 (0.53) | G6PC1OPRM1OPRD1OPRK1 | |
| SCHEMBL9016960 | 0.68 | OPRM1 (0.53) | G6PC1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5290940-A | 2,6-diarylpiperidin-1-yl substituted 2-butene stabilizers | CIBA-GEIGY CORPORATION (US) | 1994-03-01 | — | — | US | claimed |
| EP-0521820-B1 | 2,6-Diarylpiperidin-1-yl substituted 2-butene stabilizers | CIBA GEIGY AG (CH) | 1996-02-07 | — | — | EP | disclosed |
| US-5290940-A | 2,6-diarylpiperidin-1-yl substituted 2-butene stabilizers | CIBA-GEIGY CORPORATION (US) | 1994-03-01 | — | — | US | disclosed |
| US-5204474-A | Providing polymers with oxidation, heat and radiation resistances | CIBA-GEIGY CORPORATION (US) | 1993-04-20 | — | — | US | disclosed |
| EP-0521820-A1 | 2,6-Diarylpiperidin-1-yl substituted 2-butene stabilizers | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | disclosed |