Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.48 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443000 | 0.87 | TSHR (0.49) | ALDH1A1HPGDKDM4EAKR1C3AKR1C2 | |
| SCHEMBL5789105 | 0.79 | AKR1C4 (0.55) | ALDH1A1HPGDKDM4ENPSR1AKR1C3 | |
| SCHEMBL11026935 | 0.79 | CTSB (0.53) | ALDH1A1KDM4ENPSR1AKR1C3AKR1C2 | |
| SCHEMBL29272663 | 0.78 | CASP6 (0.49) | ALDH1A1KDM4EAKR1C3AKR1C2AKR1C4 | |
| SCHEMBL3741758 | 0.77 | KDM4E (0.60) | ALDH1A1HPGDKDM4ENPSR1MEN1 | |
| SCHEMBL8527632 | 0.76 | HTT (0.42) | ALDH1A1HPGDMEN1KMT2ADRD2 | |
| SCHEMBL8525974 | 0.76 | PRMT5 (0.51) | ALDH1A1HPGDKDM4ELMNADRD2 | |
| SCHEMBL2131809 | 0.76 | KDM4E (0.59) | ALDH1A1HPGDKDM4ENPSR1DRD2 | |
| SCHEMBL8416055 | 0.76 | TDP1 (0.58) | ALDH1A1HPGDKDM4EAKR1C3AKR1C2 | |
| SCHEMBL8966782 | 0.76 | KDM4E (0.59) | ALDH1A1HPGDKDM4ENPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585116-B1 | 1-Alkoxy-naphthalene-2-carboxamide derivatives with high affinity for the serotonin 5-HT1A receptor | LILLY INDUSTRIES LTD (GB) | 1996-02-28 | — | — | EP | disclosed |
| US-5389684-A | Treats disorder of central nervous system | LILLY INDUSTRIES LIMITED (GB) | 1995-02-14 | — | — | US | disclosed |
| EP-0585116-A1 | 1-Alkoxy-naphthalene-2-carboxamide derivatives with high affinity for the serotonin 5-HT1A receptor | LILLY INDUSTRIES LIMITED (GB) | 1994-03-02 | — | — | EP | disclosed |