Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21199897 | 0.86 | AOC3 (0.53) | AOC3L3MBTL1RAB9AKMT2ANPSR1 | |
| SCHEMBL21199833 | 0.85 | ALOX15 (0.52) | AOC3L3MBTL1ALDH1A1KMT2AHTT | |
| SCHEMBL28638555 | 0.84 | FFAR1 (0.55) | AOC3L3MBTL1KMT2AHTTFFAR1 | |
| SCHEMBL10877844 | 0.84 | MAPT (0.44) | L3MBTL1ALDH1A1RAB9AHTTLMNA | |
| SCHEMBL22813674 | 0.84 | ADRB1 (0.47) | AOC3L3MBTL1ALDH1A1RAB9AKMT2A | |
| SCHEMBL17754960 | 0.82 | RAB9A (0.51) | AOC3L3MBTL1ALDH1A1RAB9AKMT2A | |
| SCHEMBL8589119 | 0.82 | L3MBTL1 (0.61) | AOC3L3MBTL1ALDH1A1RAB9AKMT2A | |
| SCHEMBL7624631 | 0.82 | KCNA5 (0.50) | L3MBTL1ALDH1A1RAB9AKMT2AMEN1 | |
| SCHEMBL11468345 | 0.81 | AOC3 (0.55) | AOC3L3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL5468798 | 0.81 | AOC3 (0.57) | AOC3L3MBTL1ALDH1A1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110143878-B | Preparation method of methyl p-methoxycinnamate | 万华化学集团股份有限公司 | 2021-10-22 | — | — | CN | disclosed |
| US-10934531-B2 | Method for enantioselective carbene C—H insertion using an iron-containing protein catalyst | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2021-03-02 | — | — | US | disclosed |
| US-20190276805-A1 | METHOD FOR ENANTIOSELECTIVE CARBENE C-H INSERTION USING AN IRON-CONTAINING PROTEIN CATALYST | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-09-12 | — | — | US | disclosed |
| EP-0490198-B1 | Process for the preparation of 3-aryle acrylic acids and their derivatives | BASF AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| US-5359122-A | Preparation of 3-arylacrylic acids and their derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1994-10-25 | — | — | US | disclosed |
| EP-0490198-A2 | Process for the preparation of 3-aryle acrylic acids and their derivatives | BASF Aktiengesellschaft (DE) | 1992-06-17 | — | — | EP | disclosed |