Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR3A | P46098 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5832234 | 0.79 | KMT2A (0.41) | HAO1ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL18301198 | 0.78 | HAO1 (0.42) | HAO1TSHRMCHR1ACHEALDH1A1 | |
| Bromide SCHEMBL11705855 | 0.76 | HAO1 (0.41) | HAO1TSHRMCHR1ACHEALDH1A1 | |
| SCHEMBL8967161 | 0.74 | MAOA (0.41) | ALDH1A1MAPTMEN1KMT2AIDO1 | |
| SCHEMBL8043276 | 0.70 | ACHE (0.43) | HAO1TSHRMCHR1ACHEALDH1A1 | |
| SCHEMBL29296553 | 0.69 | ALDH1A1 (0.49) | TSHRMCHR1ACHEALDH1A1L3MBTL1 | |
| SCHEMBL20282074 | 0.69 | HPGD (0.41) | ALDH1A1HTTP2RX7 | |
| SCHEMBL576094 | 0.69 | ACHE (0.53) | HAO1TSHRMCHR1ACHEALDH1A1 | |
| SCHEMBL30310011 | 0.68 | HPGD (0.49) | HAO1ACHEALDH1A1L3MBTL1MAPT | |
| SCHEMBL20627334 | 0.68 | MAOA (0.44) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0553081-B1 | PESTICIDES | ROUSSEL UCLAF (FR) | 1996-02-28 | — | — | EP | disclosed |
| US-5326755-A | Contain cyclopropane ring | ROUSSEL UCLAF | 1994-07-05 | — | — | US | disclosed |
| EP-0553081-A1 | PESTICIDES. | ROUSSEL UCLAF (FR) | 1993-08-04 | — | — | EP | disclosed |
| WO-1991016301-A1 | PESTICIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-10-31 | — | — | WO | disclosed |