Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20282318 | 0.81 | BACE1 (0.41) | KMT2ALMNAL3MBTL1POLBBACE1 | |
| SCHEMBL8967678 | 0.79 | HAO1 (0.39) | KMT2ALMNAL3MBTL1HAO1SMN1; SMN2 | |
| SCHEMBL8967161 | 0.72 | MAOA (0.41) | KMT2ASMN1; SMN2ALDH1A1HPGDTAAR1 | |
| SCHEMBL13143422 | 0.71 | BACE1 (0.47) | KMT2ALMNAL3MBTL1POLBBACE1 | |
| SCHEMBL575956 | 0.67 | HAO1 (0.52) | LMNAHAO1TAAR1GAAAPOBEC3A | |
| SCHEMBL23048519 | 0.67 | BACE1 (0.40) | KMT2ALMNAL3MBTL1POLBHAO1 | |
| SCHEMBL19361748 | 0.67 | POLB (0.39) | LMNAL3MBTL1POLBHAO1BACE1 | |
| SCHEMBL5832257 | 0.67 | L3MBTL1 (0.57) | KMT2ALMNAL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20627334 | 0.67 | MAOA (0.44) | LMNA | |
| SCHEMBL5677326 | 0.66 | ALDH1A1 (0.46) | KMT2ALMNAL3MBTL1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084164-B2 | Triazole derivative | ASTELLAS PHARMA, INC. (JP) | 2006-08-01 | — | — | US | disclosed |
| US-7034047-B2 | Triazole derivative | ASTELLAS PHARMA, INC. (JP) | 2006-04-25 | — | — | US | disclosed |
| US-20060025461-A1 | Triazole derivative | ASTELLAS PHARMA INC. | 2006-02-02 | — | — | US | disclosed |
| US-20040214818-A1 | Triazole derivative | YAMANOUCHI PHARMACEUTICAL CO., LTD., MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG | 2004-10-28 | — | — | US | disclosed |
| EP-1293503-A1 | TRIAZOLE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2003-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214818-A1 | Triazole derivative | SLC18A3, SLC6A3, SLC18A2 | KMT2A 2031/4885LMNA 4211/4885L3MBTL1 1494/4885 |
| US-20060025461-A1 | Triazole derivative | SLC18A3, SLC6A3, SLC18A2 | KMT2A 2031/4885LMNA 4211/4885L3MBTL1 1494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.