SCHEMBL8967734

SCHEMBL8967734

CC(C=C[C@]1(F)CC1c1ccc(Cl)c(Cl)c1)=CC(=O)NSc1ccccc1C

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.32
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9455335 0.84 MMP1 (0.36) MAOB
SCHEMBL9455450 0.81 MMP1 (0.38) SLC6A2SLC6A4SLC6A3
SCHEMBL27364424 0.81 MMP1 (0.38) SLC6A2SLC6A4SLC6A3
SCHEMBL8967676 0.79
SCHEMBL8967697 0.78 RXRA (0.44) SLC6A2SLC6A4SLC6A3
SCHEMBL8967736 0.77 NPSR1 (0.38) SLC6A2SLC6A4SLC6A3
SCHEMBL9400348 0.77 NPSR1 (0.38) SLC6A2SLC6A4SLC6A3
SCHEMBL9515730 0.77 MEN1 (0.34) SLC6A2SLC6A4SLC6A3
SCHEMBL9515299 0.77 HPGD (0.40) SLC6A2SLC6A4SLC6A3
SCHEMBL27359328 0.76 F11 (0.32) SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0553081-B1 PESTICIDES ROUSSEL UCLAF (FR) 1996-02-28 EP disclosed