Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCN4 | Q9Y3Q4 | 4/20 | 0.42 |
| ▸ | HCN1 | O60741 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CDC25B | P30305 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555066 | 0.75 | CTSB (0.45) | MAPTTDP1MEN1KMT2ARAB9A | |
| SCHEMBL8967617 | 0.73 | TUBB3 (0.38) | HCN4HCN1TP53MAPTFTO | |
| SCHEMBL8553639 | 0.70 | TDP1 (0.44) | MAPTTDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL8968027 | 0.70 | TUBB3 (0.36) | HCN4HCN1TP53MAPTFTO | |
| SCHEMBL8554926 | 0.68 | HSP90AA1 (0.42) | TP53MAPTMEN1KMT2ACRHBP | |
| SCHEMBL20653820 | 0.67 | KMT2A (0.46) | MAPTFTOMEN1KMT2AGAA | |
| SCHEMBL18458726 | 0.67 | ACHE (0.59) | TP53L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL8555791 | 0.66 | MAPT (0.47) | MAPTTDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL8852163 | 0.65 | CDC25B (0.54) | MAPTMEN1KMT2ACDC25B | |
| SCHEMBL809077 | 0.65 | CDC25B (0.58) | MAPTMEN1KMT2ACDC25BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647642-A1 | 1-Azabicyclo(3.3.0)octane derivatives and their use | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1995-04-12 | — | — | EP | claimed |
| US-5530138-A | A PYRROLIZINE DERIVATIVE; EFFECTIVE IN THE TREATMENT OF SENILE DEMENTIA | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1996-06-25 | — | — | US | disclosed |
| EP-0647642-A1 | 1-Azabicyclo(3.3.0)octane derivatives and their use | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1995-04-12 | — | — | EP | disclosed |