Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MERTK | Q12866 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.37 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11583829 | 0.84 | GPR35 (0.56) | VCAM1TSHRMAPK1ALDH1A1MERTK | |
| SCHEMBL14825528 | 0.82 | VCAM1 (0.47) | VCAM1TSHRMAPK1ALDH1A1MERTK | |
| SCHEMBL25329697 | 0.78 | VCAM1 (0.47) | VCAM1ALDH1A1MERTKTDP1NPC1 | |
| SCHEMBL952362 | 0.75 | ALDH1A1 (0.45) | TSHRMAPK1ALDH1A1GPR35MAPT | |
| SCHEMBL5035508 | 0.75 | ALDH1A1 (0.59) | VCAM1TSHRALDH1A1TDP1GPR35 | |
| SCHEMBL2950121 | 0.74 | VCAM1 (0.50) | VCAM1TSHRMAPK1ALDH1A1MERTK | |
| SCHEMBL31419521 | 0.74 | VCAM1 (0.64) | VCAM1TSHRMAPK1ALDH1A1TDP1 | |
| SCHEMBL11504122 | 0.74 | VCAM1 (0.64) | VCAM1TSHRMAPK1ALDH1A1TDP1 | |
| SCHEMBL21957846 | 0.74 | VCAM1 (0.50) | VCAM1TSHRMAPK1ALDH1A1MERTK | |
| SCHEMBL6186068 | 0.74 | ALDH1A1 (0.58) | VCAM1TSHRMAPK1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| EP-0597956-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-05-25 | — | — | EP | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |