Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968876 | 0.78 | MEN1 (0.37) | KDM4EPKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8968707 | 0.77 | KDM4E (0.33) | KDM4EPKMMEN1KMT2ANQO2 | |
| SCHEMBL8968465 | 0.77 | LDHA (0.48) | KDM4EPKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL542873 | 0.77 | KDM4E (0.50) | KDM4EPKMMEN1KMT2ATP53 | |
| Dimethylamine SCHEMBL9504815 | 0.75 | KDM4E (0.46) | KDM4EPKMMEN1KMT2ATP53 | |
| SCHEMBL9770385 | 0.75 | KDM4E (0.46) | KDM4EPKMMEN1KMT2ATP53 | |
| SCHEMBL8419889 | 0.73 | LMNA (0.47) | KDM4ESMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL2544650 | 0.73 | LMNA (0.36) | KDM4EPKMMEN1KMT2ANQO2 | |
| SCHEMBL5283963 | 0.73 | TDP1 (0.58) | KDM4EPKMSMN1; SMN2MEN1KMT2A | |
| Methylamine SCHEMBL10763289 | 0.72 | KDM4E (0.47) | KDM4EPKMMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |