Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969755 | 0.89 | EGFR (0.35) | BCHEACHECHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8969540 | 0.83 | BCHE (0.32) | BCHEACHE | |
| SCHEMBL8969704 | 0.78 | HTR2C (0.36) | MAPK1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL8968877 | 0.74 | PDE3B (0.33) | BCHEACHE | |
| SCHEMBL8969988 | 0.71 | CHRNB2 (0.35) | ACHECHRNB2CHRNA7CHRNA4 | |
| SCHEMBL8968867 | 0.68 | MAPK1 (0.32) | MAPK1 | |
| SCHEMBL8968722 | 0.66 | ACHE (0.30) | ACHE | |
| SCHEMBL8969705 | 0.65 | ACHE (0.68) | MAPK1BCHEACHECCR3 | |
| SCHEMBL8968393 | 0.64 | ACHE (0.70) | MAPK1BCHEACHE | |
| SCHEMBL9385466 | 0.62 | CHRNB2 (0.35) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |