Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.30 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.30 |
| ▸ | KCNK4 | Q9NYG8 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1538338 | 0.84 | HTR2A (0.35) | CYP3A4TSHRALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL3849541 | 0.76 | TRPA1 (0.31) | — | |
| SCHEMBL28134334 | 0.76 | BACE1 (0.33) | HCAR2ALDH1A1 | |
| SCHEMBL3844515 | 0.72 | ALOX5 (0.38) | ALDH1A1 | |
| SCHEMBL29639106 | 0.70 | HTR5A (0.35) | TDP1 | |
| SCHEMBL926937 | 0.70 | HTR5A (0.35) | TDP1 | |
| Hydrochloric Acid SCHEMBL30881482 | 0.68 | HTR5A (0.34) | TDP1 | |
| Iodide SCHEMBL29258426 | 0.68 | HTR5A (0.37) | TDP1 | |
| SCHEMBL12502556 | 0.67 | LMNA (0.34) | CYP3A4TSHRALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL11847844 | 0.67 | MAPK1 (0.36) | HCAR2CYP3A4TSHRALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104804004-B | A kind of preparation method of chiral hexahydropyrrolo diindyl class compound | 安徽师范大学 | 2017-03-29 | — | — | CN | disclosed |
| CN-104804004-A | Preparation method of chiral hexahydropyrroloindole compound | UNIV ANHUI NORMAL | 2015-07-29 | — | — | CN | disclosed |
| US-4273862-A | ANIONIC CYANINE DYE, HYDROQUINONE FRBRLOPRT | MITSUBISHI PAPER MILLS, LTD. (JP) | 1981-06-16 | — | — | US | disclosed |
| US-4259439-A | DIMETHINECYANINE DYE SENSITIZER | MITSUBISHI PAPER MILLS, LTD. (JP) | 1981-03-31 | — | — | US | disclosed |
| US-4175965-A | SILVER HALIDE EMULSION CONTAINING AN ELECTRON ACCEPTOR AND A SENSITIZING DYE | MITSUBISHI PAPER MILLS, LTD. (JP) | 1979-11-27 | — | — | US | disclosed |
| US-4147554-A | 5,6-DIHYDRO-PYRROLO(2,1-A)ISOQUINOLINES | MITSUBISHI PAPER MILLS, LTD. (JP) | 1979-04-03 | — | — | US | disclosed |
| US-4115122-A | Internal latent image silver halide emulsion containing a heterocyclic quaternary salt having a propargyl or a butyryl containing substituent | FUJI PHOTO FILM CO., LTD. (JP) | 1978-09-19 | — | — | US | disclosed |
| US-4094683-A | HETEROCYCLIC QUATERNARY AMMONIUM COMPOUND AS FOGGING AGENT | FUJI PHOTO FILM CO., LTD. (JA) | 1978-06-13 | — | — | US | disclosed |
| US-4053318-A | SENSITIZING MEROCYANINE DYE | FUJI PHOTO FILM CO., LTD. (JA) | 1977-10-11 | — | — | US | disclosed |
| US-4018610-A | Supersensitized silver halide photographic emulsion | FUJI PHOTO FILM CO., LTD. (JA) | 1977-04-19 | — | — | US | disclosed |