Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 10/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.33 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969639 | 0.83 | OPRL1 (0.33) | CTSDOPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL8969723 | 0.83 | HTR2C (0.36) | OPRL1OPRM1HTR2CHTR2AHTR2B | |
| SCHEMBL8969189 | 0.82 | ACHE (0.39) | ACHECTSDHTR2CHTR2AHTR2B | |
| SCHEMBL8968664 | 0.81 | KLK7 (0.32) | HTR2CHTR2A | |
| SCHEMBL8969666 | 0.80 | CTSD (0.34) | CTSDOPRL1OPRM1HTR2CHTR2A | |
| SCHEMBL8970030 | 0.79 | CTSD (0.50) | ACHECTSDOPRL1OPRM1OPRD1 | |
| SCHEMBL8969039 | 0.78 | OPRM1 (0.31) | OPRL1OPRM1 | |
| SCHEMBL8969608 | 0.76 | OPRM1 (0.33) | OPRL1OPRM1 | |
| SCHEMBL8970140 | 0.74 | CTSD (0.32) | CTSD | |
| SCHEMBL8968500 | 0.73 | NOS1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |