Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 7/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8419659 | 0.84 | KDM4E (0.39) | GABRA1GABRB2ALOX5CNR2L3MBTL1 | |
| SCHEMBL8969225 | 0.79 | ALDH1A1 (0.36) | GABRA1GABRB2ALOX5CNR2L3MBTL1 | |
| SCHEMBL8418566 | 0.78 | FDFT1 (0.45) | GABRA1GABRB2ALOX5L3MBTL1LMNA | |
| SCHEMBL27460107 | 0.77 | APP (0.44) | GABRA1GABRB2ALOX5L3MBTL1LMNA | |
| SCHEMBL8419836 | 0.76 | ALOX5 (0.41) | GABRA1GABRB2ALOX5CNR2L3MBTL1 | |
| SCHEMBL8418604 | 0.76 | ELANE (0.40) | GABRA1GABRB2ALOX5CNR2L3MBTL1 | |
| SCHEMBL8422008 | 0.76 | PPARA (0.49) | PPARGPPARDPPARA | |
| SCHEMBL8417976 | 0.76 | PPARA (0.42) | ALOX5PPARDPPARAPTGDRPTGDR2 | |
| SCHEMBL8969517 | 0.76 | CYP4Z1 (0.40) | ALOX5L3MBTL1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL27460108 | 0.75 | ALOX5 (0.36) | GABRA1GABRB2ALOX5CNR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |