Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.38 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970442 | 0.78 | KDM4E (0.30) | ACHEMAOAALDH1A1 | |
| SCHEMBL8969417 | 0.78 | MAOA (0.36) | ACHEMAOA | |
| SCHEMBL8969002 | 0.75 | ACHE (0.39) | ACHEALDH1A1PTGS1HSD17B10 | |
| SCHEMBL8969217 | 0.74 | PDE3B (0.43) | ALDH1A1HSD17B10 | |
| SCHEMBL8969665 | 0.72 | ACHE (0.48) | ACHEMAOAALDH1A1 | |
| SCHEMBL8969302 | 0.72 | ACHE (0.50) | ACHEMAOAALDH1A1 | |
| SCHEMBL8968414 | 0.71 | ACHE (0.36) | ACHEMAOA | |
| SCHEMBL8968801 | 0.70 | ACHE (0.36) | ACHEMAOA | |
| SCHEMBL8969986 | 0.70 | MAOA (0.35) | ACHEMAOAALDH1A1 | |
| SCHEMBL8968208 | 0.69 | PDE3B (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |