Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 14/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.39 |
| ▸ | AR | P10275 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233426 | 0.89 | SHBG (0.36) | ESR1ESR2 | |
| SCHEMBL72006 | 0.82 | TP53 (0.50) | ESR1ESR2ARTP53TDP1 | |
| SCHEMBL7916409 | 0.80 | ESR1 (0.48) | ESR1ESR2AR | |
| SCHEMBL13799732 | 0.75 | ESR1 (0.44) | ESR1ESR2ARTP53TDP1 | |
| SCHEMBL13799738 | 0.74 | ESR1 (0.43) | ESR1ESR2AR | |
| SCHEMBL8575329 | 0.73 | SHBG (0.37) | ESR1ESR2 | |
| SCHEMBL15933317 | 0.73 | HSD17B1 (0.35) | ESR1ESR2 | |
| SCHEMBL19314239 | 0.72 | TP53 (0.41) | ESR1ESR2ARTP53TDP1 | |
| SCHEMBL727419 | 0.72 | CA1 (0.50) | ESR1ESR2 | |
| SCHEMBL9297246 | 0.70 | ALOX5 (0.46) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699702-A2 | Reaction products of carbonyl compounds and dihydric phenols | THE DOW CHEMICAL COMPANY (US) | 1996-03-06 | — | — | EP | disclosed |