Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.30 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968721 | 0.85 | KDM4E (0.38) | HRH4ALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL8968606 | 0.84 | ACHE (0.39) | — | |
| SCHEMBL8969708 | 0.81 | ALDH1A1 (0.38) | ALDH1A1CYP2C19 | |
| SCHEMBL8968188 | 0.79 | ACHE (0.32) | — | |
| SCHEMBL8968555 | 0.74 | MPO (0.36) | HRH4 | |
| SCHEMBL8969462 | 0.70 | PIK3CD (0.31) | — | |
| SCHEMBL8969661 | 0.69 | BCHE (0.34) | HRH4ALDH1A1 | |
| SCHEMBL8969422 | 0.69 | HRH4 (0.34) | HRH4 | |
| SCHEMBL8969894 | 0.69 | KDM4E (0.38) | HRH4ALDH1A1 | |
| SCHEMBL8968270 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |