Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969988 | 0.83 | CHRNB2 (0.35) | ACHE | |
| SCHEMBL8969113 | 0.78 | CTSD (0.32) | — | |
| SCHEMBL8968722 | 0.77 | ACHE (0.30) | ACHE | |
| SCHEMBL8968877 | 0.71 | PDE3B (0.33) | ACHE | |
| SCHEMBL8969540 | 0.71 | BCHE (0.32) | ACHE | |
| SCHEMBL8969615 | 0.68 | CTSD (0.30) | — | |
| SCHEMBL8968819 | 0.66 | MAPK1 (0.34) | ACHE | |
| SCHEMBL8968700 | 0.64 | ACHE (0.70) | ACHE | |
| SCHEMBL4927003 | 0.64 | PDE3B (0.60) | — | |
| SCHEMBL8968432 | 0.61 | CTSD (0.48) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |