SCHEMBL8970313

SCHEMBL8970313

CCC(C)CCOC(=O)C1CSCC1C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.33
PPM1B O75688 1/20 0.31
PTPN1 P18031 1/20 0.31
PPP1CC P36873 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8969484 0.85 ALOX15 (0.33)
SCHEMBL8970499 0.81 PPM1B (0.45) PPARGPPM1BPTPN1PPP1CC
SCHEMBL8969248 0.79 GRM2 (0.31)
SCHEMBL8970764 0.79 GPR88 (0.30)
SCHEMBL8969294 0.78 ALDH1A1 (0.41) PPARGPPM1BPTPN1PPP1CC
SCHEMBL8970200 0.77 PPM1B (0.42) PPM1BPTPN1PPP1CC
SCHEMBL8970154 0.77 PPARG (0.43) PPARG
SCHEMBL8971023 0.76 RAB9A (0.39)
SCHEMBL8971150 0.76 PPARG (0.45) PPARG
SCHEMBL8970238 0.76 PPARG (0.45) PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0376294-B1 Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions HITACHI LTD (JP) 1996-03-13 EP disclosed
US-5370821-A Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-12-06 US disclosed
US-5269965-A Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions TAKEDA CHEMICAL INDUSTRIES (JP) 1993-12-14 US disclosed
EP-0376294-A1 Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions HITACHI, LTD. (JP) 1990-07-04 EP disclosed