Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 15/20 | 0.37 |
| ▸ | BCHE | P06276 | 10/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957840 | 0.76 | RXRB (0.41) | ACHEBCHEALDH1A1TDP1 | |
| SCHEMBL8097787 | 0.72 | TSHR (0.40) | ACHEBCHEALDH1A1TDP1 | |
| SCHEMBL7077835 | 0.71 | ACHE (0.38) | ACHEBCHE | |
| SCHEMBL7056142 | 0.68 | HTR2A (0.40) | ACHEBCHE | |
| SCHEMBL12668863 | 0.68 | ACHE (0.40) | ACHEBCHE | |
| SCHEMBL22568907 | 0.67 | ACHE (0.49) | ACHEBCHE | |
| SCHEMBL6952658 | 0.67 | ADRA2A (0.40) | ACHEBCHE | |
| SCHEMBL12635266 | 0.67 | CA12 (0.45) | ACHEBCHEALDH1A1 | |
| SCHEMBL9361563 | 0.66 | ACHE (0.46) | ACHEBCHE | |
| SCHEMBL11801209 | 0.65 | ALDH1A1 (0.53) | ALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585392-A | TREATING OR PREVENTING STROKES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| US-5506246-A | Method for treating depression using substituted aminomethyltetralins and their heterocyclic analogues | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-09 | — | — | US | disclosed |
| EP-0352613-B1 | Substituted amino methyl tetralines, and their heterocyclic analogous compounds | BAYER AG (DE) | 1994-04-20 | — | — | EP | disclosed |
| US-5300523-A | Binding serotonin receptors, treating nervous system disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-05 | — | — | US | disclosed |
| US-5137901-A | For binding 5-HT 1 receptors; treating central nervous system disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-11 | — | — | US | disclosed |
| EP-0352613-A2 | Substituted amino methyl tetralines, and their heterocyclic analogous compounds | BAYER AG (DE) | 1990-01-31 | — | — | EP | disclosed |