Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091499 | 0.85 | NLRP3 (0.40) | MAPTALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL6957840 | 0.84 | RXRB (0.41) | TSHRMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL8097781 | 0.83 | ADRA2A (0.43) | TSHRALDH1A1POLBMEN1KMT2A | |
| SCHEMBL8097604 | 0.83 | ADRA2A (0.43) | MAPTALDH1A1HPGDPOLBLMNA | |
| SCHEMBL8091366 | 0.78 | NOTUM (0.43) | TSHRALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL8096734 | 0.73 | PPARG (0.42) | TSHRMAPTALDH1A1HPGDRAB9A | |
| SCHEMBL18277350 | 0.73 | TSHR (0.50) | TSHRMAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL8970487 | 0.72 | ACHE (0.37) | ALDH1A1BCHEACHETDP1 | |
| SCHEMBL8092437 | 0.71 | ADRA2A (0.43) | TSHRMAPTNPSR1HPGDPOLB | |
| SCHEMBL12668863 | 0.71 | ACHE (0.40) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127396-A | Imidazoline compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |