Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.38 |
| ▸ | BCHE | P06276 | 5/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6951348 | 0.82 | SCN4A (0.31) | — | |
| SCHEMBL6955284 | 0.79 | ADRA2A (0.46) | — | |
| SCHEMBL6957278 | 0.79 | ADRA2A (0.46) | — | |
| SCHEMBL6957840 | 0.72 | RXRB (0.41) | ACHEBCHE | |
| SCHEMBL6960771 | 0.72 | HTR2A (0.42) | ACHEHTR2ADRD2DRD3 | |
| SCHEMBL6954590 | 0.72 | HTR2A (0.42) | ACHEHTR2ADRD2DRD3 | |
| SCHEMBL8970487 | 0.71 | ACHE (0.37) | ACHEBCHE | |
| SCHEMBL6958705 | 0.70 | CYP11B2 (0.41) | HTR2ADRD2DRD3 | |
| SCHEMBL7056142 | 0.70 | HTR2A (0.40) | ACHEBCHEHTR2ADRD2DRD3 | |
| SCHEMBL8097787 | 0.68 | TSHR (0.40) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1010693-B1 | Imidazoline derivatives, preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-09-24 | — | — | EP | disclosed |
| US-6127396-A | Imidazoline compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |