Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MITF | O75030 | 2/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | RNF4 | P78317 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970273 | 0.89 | THRB (0.40) | NPC1RAB9AMITFXBP1NPSR1 | |
| SCHEMBL8428153 | 0.86 | NPC1 (0.58) | NPC1RAB9AMITFXBP1NPSR1 | |
| SCHEMBL14301433 | 0.80 | RAB9A (0.52) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8426259 | 0.80 | THRB (0.50) | NPC1RAB9AMITFXBP1NPSR1 | |
| SCHEMBL9151730 | 0.78 | ALDH1A1 (0.46) | RAB9AALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL29128664 | 0.78 | MEN1 (0.58) | NPC1RAB9AMITFXBP1NPSR1 | |
| SCHEMBL6688408 | 0.78 | CA12 (0.47) | NPC1RAB9AMITFXBP1NPSR1 | |
| SCHEMBL11541521 | 0.78 | SMN1; SMN2 (0.59) | NPC1RAB9AMITFNPSR1RNF4 | |
| SCHEMBL12961083 | 0.74 | ALDH1A1 (0.58) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL5082916 | 0.74 | SMN1; SMN2 (0.65) | NPC1RAB9ANPSR1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337785-B2 | Diagnostic kit and method for rapid detection of antibodies | JOHNSON & JOHNSON CLIN DIAG (US) | 1996-03-13 | — | — | EP | disclosed |
| EP-0468584-B1 | Copolymers containing polyoxyalkylene side chains | EASTMAN KODAK CO (US) | 1995-01-18 | — | — | EP | disclosed |
| US-5374516-A | Covalently attached to polymer particles of ethylenically unsaturated monomers with reactive alkylsulfonyl or halogen groups; detecting hormones, drugs, steroids in urine, blood, saliva | EASTMAN KODAK COMPANY (US) | 1994-12-20 | — | — | US | disclosed |
| EP-0347137-B1 | Microporous article having a stabilized specific binding reagent, a method for its use and a diagnostic test kit | EASTMAN KODAK CO (US) | 1994-07-27 | — | — | EP | disclosed |
| EP-0525916-A1 | Diluent composition | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1993-02-03 | — | — | EP | disclosed |
| US-5155021-A | METHOD AND KIT FOR DETERMINATION OF HERPES SIMPLEX VIRAL ANTIGEN BY DIRECT BINDING TO POLYMERIC PARTICLES | EASTMAN KODAK COMPANY (US) | 1992-10-13 | — | — | US | disclosed |
| US-5149416-A | Water soluble, crosslinked acrylamide bases copolymer | EASTMAN KODAK COMPANY (US) | 1992-09-22 | — | — | US | disclosed |
| US-5086143-A | COPOLYMERS CONTAINING POLYOXYALKYLENE SIDE CHAINS | EASTMAN KODAK COMPANY (US) | 1992-02-04 | — | — | US | disclosed |
| EP-0468584-A2 | Copolymers containing polyoxyalkylene side chains | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-01-29 | — | — | EP | disclosed |
| US-5073603-A | Acrylamide-based | EASTMAN KODAK COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| EP-0347137-A2 | Microporous article having a stabilized specific binding reagent, a method for its use and a diagnostic test kit | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-12-20 | — | — | EP | disclosed |
| WO-1989009939-A1 | COMPOSITIONS, DIAGNOSTIC KIT AND METHOD FOR RAPID DETECTION OF ANTIBODIES | EASTMAN KODAK COMPANY (US) | 1989-10-19 | — | — | WO | disclosed |
| EP-0337785-A1 | Diagnostic kit and method for rapid detection of antibodies | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1989-10-18 | — | — | EP | disclosed |