Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | MLYCD | O95822 | 1/20 | 0.68 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.65 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.65 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.65 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | AHR | P35869 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29989592 | 0.87 | RAB9A (0.77) | MLYCDPABPC1APOBEC3AEIF4HAPOBEC3G | |
| SCHEMBL527994 | 0.87 | RAB9A (0.77) | MLYCDPABPC1APOBEC3AEIF4HAPOBEC3G | |
| SCHEMBL9620767 | 0.86 | MLYCD (0.69) | GAAMLYCDPABPC1APOBEC3AEIF4H | |
| SCHEMBL16583906 | 0.86 | RAB9A (0.70) | MLYCDPABPC1APOBEC3AEIF4HAPOBEC3G | |
| SCHEMBL8970971 | 0.86 | POLB (0.70) | MLYCDPABPC1APOBEC3AEIF4HAPOBEC3G | |
| SCHEMBL9620772 | 0.86 | F10 (0.81) | GAAMLYCDPABPC1APOBEC3AEIF4H | |
| SCHEMBL96146 | 0.84 | MLYCD (0.68) | GAAMLYCDPABPC1APOBEC3AEIF4H | |
| SCHEMBL10605968 | 0.84 | GAA (0.66) | GAAHDAC1KMT2AMEN1HDAC8 | |
| SCHEMBL345880 | 0.84 | MAPT (0.63) | GAAKMT2AMEN1AHRHPGD | |
| SCHEMBL31467959 | 0.84 | GAA (0.80) | GAAHDAC1KMT2AMEN1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023340-B2 | Wnt inhibitors for human stem cell differentiation | CHEMREGEN, INC. (US) | 2015-05-05 | — | — | US | disclosed |
| US-20130177535-A1 | WNT INHIBITORS FOR HUMAN STEM CELL DIFFERENTIATION | CHEMREGEN, INC | 2013-07-11 | — | — | US | disclosed |
| US-20110269758-A1 | NAPHTHYRIDINONES AS PROTEIN KINASE INHIBITORS | MERCK PATENT GMBH (DE) | 2011-11-03 | — | — | US | disclosed |
| US-20110269758-A1 | NAPHTHYRIDINONES AS PROTEIN KINASE INHIBITORS | MERCK PATENT GMBH (DE) | 2011-11-03 | — | — | US | disclosed |
| WO-2010002779-A2 | NAPHTHYRIDININONES AS AURORA KINASE INHIBITORS | MERCK SERONO S.A. (CH) | 2010-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269758-A1 | NAPHTHYRIDINONES AS PROTEIN KINASE INHIBITORS | AURKA, AURKC, AURKB | GAA 1900/4885MLYCD 3147/4885PABPC1 1723/4885 |
| US-20130177535-A1 | WNT INHIBITORS FOR HUMAN STEM CELL DIFFERENTIATION | WNT3A, WNT1, WNT3 | GAA 2462/4885MLYCD 4001/4885PABPC1 3691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.