SCHEMBL8972571

SCHEMBL8972571

CC(C)C1CCC(C)(c2ccc(Oc3cccc(N)c3)cc2)C(c2ccc(Oc3cccc(N)c3)cc2)C1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.40
ALDH1A1 P00352 5/20 0.38
ATM Q13315 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MAPT P10636 2/20 0.35
MEN1 O00255 1/20 0.35
MITF O75030 1/20 0.35
GAA P10253 1/20 0.35
GFER P55789 1/20 0.35
KMT2A Q03164 1/20 0.35
NLRP1 Q9C000 1/20 0.35
NOD2 Q9HC29 1/20 0.35
LTA4H P09960 1/20 0.34
ALOX5 P09917 1/20 0.33
CYP3A4 P08684 2/20 0.32
KDM1A O60341 1/20 0.32
POLB P06746 1/20 0.32
HSP90AA1 P07900 1/20 0.32
TNK2 Q07912 1/20 0.31
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8973167 0.89 ALDH1A1 (0.35) MAOBALDH1A1SMN1; SMN2MAPTMEN1
SCHEMBL24322076 0.79 SLC6A4 (0.38) MAOBALDH1A1ATMMEN1GAA
SCHEMBL8972262 0.74 MAOB (0.35) MAOBALDH1A1GAACYP3A4KDM1A
SCHEMBL337274 0.73 KDM1A (0.40) MAOBKDM1A
SCHEMBL8972653 0.73
SCHEMBL9348587 0.71 MAOB (0.50) MAOBALDH1A1ATMSMN1; SMN2MAPT
SCHEMBL8972665 0.71
SCHEMBL8588502 0.68 MAOB (0.42) MAOBALDH1A1ATMSMN1; SMN2MAPT
SCHEMBL8972686 0.67
SCHEMBL8675186 0.67 OPRL1 (0.35) MAOBKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0710690-A2 Polyimide film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-05-08 EP disclosed
US-5498687-A Unsaturated imide compounds containing alicyclic structure, process for producing the same and intermediate therefor SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-03-12 US disclosed
US-5489669-A FORMED FROM AMINE CONTAINING BIS/4-AMINOPHENOXY/PHENYL GROUPS; SOLUBILITY, DIELECTRICS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-02-06 US disclosed
US-5444165-A Reacting diamino compound with unsaturated dicarboxylic anhydride to form amic acid intermediate, catalytic dehydration-ring closing; solvent soluble, low water absorption and flexibility SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-08-22 US disclosed
EP-0633282-A1 Polyimide and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-01-11 EP disclosed
US-5326881-A Polymers with good heat resistance, good flexibility and low water absorption SUMITOMO CHEMICAL COMPANY LTD. (JP) 1994-07-05 US disclosed
EP-0595230-A1 Unsaturated imide compounds containing alicyclic structure SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-05-04 EP disclosed