SCHEMBL8973167

SCHEMBL8973167

CC(C)C1CCC(C)(c2ccc(Oc3ccc(N)cc3)cc2)C(c2ccc(Oc3ccc(N)cc3)cc2)C1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.35
TDP1 Q9NUW8 2/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
TEAD4 Q15561 1/20 0.34
MAPT P10636 4/20 0.33
POLB P06746 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
NPC1 O15118 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
RAB9A P51151 1/20 0.32
MAOA P21397 2/20 0.32
MAOB P27338 1/20 0.31
CYP19A1 P11511 1/20 0.31
MEN1 O00255 1/20 0.30
MITF O75030 1/20 0.30
GAA P10253 1/20 0.30
GFER P55789 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8972571 0.89 MAOB (0.40) ALDH1A1CYP3A4MAPTPOLBSMN1; SMN2
SCHEMBL8196759 0.85 GAA (0.35) ALDH1A1GAA
SCHEMBL24322076 0.84 SLC6A4 (0.38) ALDH1A1RAB9AMAOAMAOBMEN1
SCHEMBL8973404 0.84
SCHEMBL8972884 0.82 ALDH1A1 (0.31) ALDH1A1TEAD4SMN1; SMN2
SCHEMBL4333830 0.79 ESR2 (0.42) CYP19A1
SCHEMBL8703035 0.76 LTA4H (0.39) ALDH1A1TDP1MAPTPOLBSMN1; SMN2
SCHEMBL337274 0.76 KDM1A (0.40) MAOAMAOBKDM1A
SCHEMBL8972653 0.74
SCHEMBL8972686 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5489669-A FORMED FROM AMINE CONTAINING BIS/4-AMINOPHENOXY/PHENYL GROUPS; SOLUBILITY, DIELECTRICS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-02-06 US claimed
EP-0633282-A1 Polyimide and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-01-11 EP claimed
JP-7026017-A None JP disclosed
EP-0710690-A2 Polyimide film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-05-08 EP disclosed
US-5498687-A Unsaturated imide compounds containing alicyclic structure, process for producing the same and intermediate therefor SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-03-12 US disclosed
US-5489669-A FORMED FROM AMINE CONTAINING BIS/4-AMINOPHENOXY/PHENYL GROUPS; SOLUBILITY, DIELECTRICS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-02-06 US disclosed
US-5444165-A Reacting diamino compound with unsaturated dicarboxylic anhydride to form amic acid intermediate, catalytic dehydration-ring closing; solvent soluble, low water absorption and flexibility SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-08-22 US disclosed
JP-H0726017-A POLYIMIDE AND ITS PRODUCTION SUMITOMO CHEM CO LTD 1995-01-27 JP disclosed
EP-0633282-A1 Polyimide and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-01-11 EP disclosed
US-5326881-A Polymers with good heat resistance, good flexibility and low water absorption SUMITOMO CHEMICAL COMPANY LTD. (JP) 1994-07-05 US disclosed
EP-0595230-A1 Unsaturated imide compounds containing alicyclic structure SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-05-04 EP disclosed