Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRK6 | P43250 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9127775 | 0.82 | L3MBTL1 (0.37) | TDP1L3MBTL1PARP1PARP10SRD5A1 | |
| SCHEMBL20596974 | 0.81 | TDP1 (0.36) | TDP1L3MBTL1PARP1PARP10SRD5A1 | |
| SCHEMBL10078298 | 0.79 | MPO (0.52) | — | |
| SCHEMBL7401882 | 0.79 | SIGMAR1 (0.45) | SRD5A1SRD5A2AKR1B1LMNA | |
| SCHEMBL9572172 | 0.77 | CYP1A2 (0.48) | AKR1B1PTGDR2MEN1KMT2AGRK6 | |
| SCHEMBL3451418 | 0.76 | AKR1B1 (0.56) | AKR1B1 | |
| Acetic Acid SCHEMBL9127778 | 0.75 | TDP1 (0.41) | TDP1L3MBTL1PARP1PARP10SRD5A1 | |
| SCHEMBL17188065 | 0.73 | TDP1 (0.41) | TDP1L3MBTL1PARP1PARP10 | |
| SCHEMBL5343932 | 0.72 | SRD5A1 (0.50) | L3MBTL1SRD5A1SRD5A2AKR1B1SLC1A3 | |
| SCHEMBL8308916 | 0.72 | RXRA (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566455-B1 | Derivatives of 7-ethynyle alpha-(methoxymethylene)1-naphthalenacetic acid, their process of preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1996-03-06 | — | — | EP | disclosed |
| EP-0566455-A1 | Derivatives of 7-ethynyle alpha-(methoxymethylene)1-naphthalenacetic acid, their process of preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1993-10-20 | — | — | EP | disclosed |
| EP-0538097-A1 | Naphthalene-1-acetic-acid derivatives, their preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1993-04-21 | — | — | EP | disclosed |