SCHEMBL8973635

SCHEMBL8973635

Cc1[nH]c(-c2ccccc2)nc1Cc1ccc(Cl)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.47
DRD4 P21917 1/20 0.47
DRD3 P35462 1/20 0.47
PIN1 Q13526 2/20 0.44
GABRA1 P14867 1/20 0.44
GABRB2 P47870 1/20 0.44
NPY5R Q15761 2/20 0.44
NR1H2 P55055 2/20 0.43
KMT2A Q03164 2/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
HPGD P15428 1/20 0.43
MAPK1 P28482 1/20 0.43
HSD17B10 Q99714 1/20 0.43
FTO Q9C0B1 1/20 0.43
NPC1 O15118 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8764478 0.89 PIN1 (0.50) DRD2DRD4DRD3PIN1NPY5R
SCHEMBL8973605 0.88 PIN1 (0.46) DRD2DRD4DRD3PIN1GABRA1
SCHEMBL8973149 0.85 MAPK13 (0.47) DRD2DRD4DRD3PIN1NPY5R
SCHEMBL8973651 0.85 ALDH1A1 (0.43) DRD2DRD4DRD3PIN1NPY5R
SCHEMBL8973218 0.81 KDM4E (0.46) DRD2DRD4DRD3PIN1NPY5R
SCHEMBL8972962 0.79 SMN1; SMN2 (0.45) DRD2DRD4DRD3PIN1NPY5R
Hydrochloric Acid SCHEMBL1436115 0.76 PIN1 (0.50) DRD2DRD4DRD3PIN1NPY5R
SCHEMBL19350079 0.76 MAPK1 (0.49) DRD2DRD4DRD3NPY5RKMT2A
SCHEMBL28412520 0.76 PIN1 (0.53) DRD2DRD4DRD3PIN1NPY5R
SCHEMBL8973612 0.76 PIN1 (0.46) DRD2DRD4DRD3PIN1NPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5560785-A TREATING SURFACE WITH SOLUTION OF IMIDAZOLE COMPOUND, COPPER COMPOUND, ZINC COMPOUND, STABILIZERS SHIKOKU CHEMICALS CORPORATION (JP) 1996-10-01 US disclosed
US-5498301-A ON A PRINTED WIRING BOARD, HEAT RESISTANT, MOISTURE RESISTANT, A 2-ARYLIMIDAZOLE, CARBOXYLIC ACID, AMMONIA, WATER SHIKOKU CHEMICALS CORPORATION (JP) 1996-03-12 US disclosed
EP-0627499-A1 Agent for treating surfaces of copper and copper alloys SHIKOKU CHEMICALS CORPORATION (JP) 1994-12-07 EP disclosed