SCHEMBL8973651

SCHEMBL8973651

Cc1[nH]c(-c2ccccc2)nc1Cc1ccc(Cl)c(Cl)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
HPGD P15428 1/20 0.43
ALOX12 P18054 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA1 P30542 1/20 0.43
MAPK13 O15264 1/20 0.42
RAF1 P04049 1/20 0.42
MAPK12 P53778 1/20 0.42
MAPK11 Q15759 1/20 0.42
MAPK14 Q16539 1/20 0.42
DRD2 P14416 1/20 0.42
DRD4 P21917 1/20 0.42
DRD3 P35462 1/20 0.42
ALKBH3 Q96Q83 1/20 0.42
SLC6A2 P23975 2/20 0.41
SLC6A4 P31645 2/20 0.41
SLC6A3 Q01959 2/20 0.41
PIN1 Q13526 2/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8973635 0.85 DRD2 (0.47) ALDH1A1HPGDMAPK13RAF1MAPK12
SCHEMBL8764478 0.82 PIN1 (0.50) ALDH1A1HPGDDRD2DRD4DRD3
SCHEMBL8973605 0.81 PIN1 (0.46) ALDH1A1HPGDDRD2DRD4DRD3
SCHEMBL8973149 0.79 MAPK13 (0.47) MAPK13MAPK12MAPK11MAPK14DRD2
SCHEMBL8972962 0.79 SMN1; SMN2 (0.45) ALDH1A1LMNAADORA2AADORA1MAPK13
SCHEMBL8973218 0.77 KDM4E (0.46) ALDH1A1LMNAHPGDDRD2DRD4
SCHEMBL26113428 0.77 RNASEH1 (0.47) ALDH1A1LMNAHPGDALOX12ADORA2A
SCHEMBL31305491 0.77 RNASEH1 (0.47) ALDH1A1LMNAHPGDALOX12ADORA2A
SCHEMBL3141258 0.74 RAF1 (0.63) LMNAMAPK13RAF1MAPK12MAPK11
SCHEMBL31305387 0.74 RAF1 (0.63) LMNAMAPK13RAF1MAPK12MAPK11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5560785-A TREATING SURFACE WITH SOLUTION OF IMIDAZOLE COMPOUND, COPPER COMPOUND, ZINC COMPOUND, STABILIZERS SHIKOKU CHEMICALS CORPORATION (JP) 1996-10-01 US disclosed
US-5498301-A ON A PRINTED WIRING BOARD, HEAT RESISTANT, MOISTURE RESISTANT, A 2-ARYLIMIDAZOLE, CARBOXYLIC ACID, AMMONIA, WATER SHIKOKU CHEMICALS CORPORATION (JP) 1996-03-12 US disclosed
EP-0627499-A1 Agent for treating surfaces of copper and copper alloys SHIKOKU CHEMICALS CORPORATION (JP) 1994-12-07 EP disclosed