SCHEMBL8973605

SCHEMBL8973605

Cc1ccc(Cc2nc(-c3ccccc3)[nH]c2C)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 1/20 0.46
DRD2 P14416 1/20 0.46
DRD4 P21917 1/20 0.46
DRD3 P35462 1/20 0.46
POLB P06746 2/20 0.43
TNKS O95271 1/20 0.43
PARP1 P09874 1/20 0.43
TNKS2 Q9H2K2 1/20 0.43
NPY5R Q15761 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
HPGDS O60760 1/20 0.43
NR1H2 P55055 1/20 0.43
NR1H3 Q13133 1/20 0.43
MAPT P10636 2/20 0.41
GAA P10253 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
GLA P06280 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8764478 0.92 PIN1 (0.50) PIN1DRD2DRD4DRD3POLB
SCHEMBL8973149 0.88 MAPK13 (0.47) PIN1DRD2DRD4DRD3POLB
SCHEMBL8973635 0.88 DRD2 (0.47) PIN1DRD2DRD4DRD3POLB
SCHEMBL8973651 0.81 ALDH1A1 (0.43) PIN1DRD2DRD4DRD3NPY5R
SCHEMBL28412520 0.78 PIN1 (0.53) PIN1DRD2DRD4DRD3POLB
SCHEMBL8973612 0.78 PIN1 (0.46) PIN1DRD2DRD4DRD3POLB
SCHEMBL1099825 0.77 PIN1 (0.56) PIN1DRD2DRD4DRD3POLB
SCHEMBL1436137 0.77 PIN1 (0.51) PIN1DRD2DRD4DRD3POLB
SCHEMBL9720872 0.77 VSIR (0.45) PIN1DRD2DRD4DRD3POLB
SCHEMBL8972962 0.76 SMN1; SMN2 (0.45) PIN1DRD2DRD4DRD3POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5560785-A TREATING SURFACE WITH SOLUTION OF IMIDAZOLE COMPOUND, COPPER COMPOUND, ZINC COMPOUND, STABILIZERS SHIKOKU CHEMICALS CORPORATION (JP) 1996-10-01 US disclosed
US-5498301-A ON A PRINTED WIRING BOARD, HEAT RESISTANT, MOISTURE RESISTANT, A 2-ARYLIMIDAZOLE, CARBOXYLIC ACID, AMMONIA, WATER SHIKOKU CHEMICALS CORPORATION (JP) 1996-03-12 US disclosed
EP-0627499-A1 Agent for treating surfaces of copper and copper alloys SHIKOKU CHEMICALS CORPORATION (JP) 1994-12-07 EP disclosed