Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 8/20 | 0.39 |
| ▸ | PPARD | Q03181 | 3/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973759 | 0.91 | POLB (0.41) | POLBKIF11PPARDGPR119MMP1 | |
| SCHEMBL8973844 | 0.88 | KIF11 (0.40) | POLBKIF11PPARDCA12CA1 | |
| SCHEMBL8974231 | 0.87 | CA9 (0.46) | POLBCA12CA1CA2CA9 | |
| SCHEMBL9117838 | 0.84 | KIF11 (0.43) | POLBKIF11CA12CA1CA2 | |
| SCHEMBL8973781 | 0.83 | KIF11 (0.59) | KIF11CA12CA1CA2MAPT | |
| SCHEMBL8974153 | 0.82 | KIF11 (0.40) | POLBKIF11PPARDCA12CA1 | |
| SCHEMBL9131829 | 0.82 | KIF11 (0.43) | POLBKIF11CA12CA1CA2 | |
| SCHEMBL8973783 | 0.81 | KIF11 (0.40) | POLBKIF11CA12CA1CA2 | |
| SCHEMBL8974753 | 0.81 | KIF11 (0.40) | POLBKIF11PPARDCA12CA1 | |
| SCHEMBL8973691 | 0.81 | CA1 (0.43) | KIF11CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576339-A | Pyridyl substituted cyclopentadienes for the treatment of inflamation | HUANG HORNG-CHIH (US) | 1996-11-19 | — | — | US | disclosed |
| US-5418254-A | Side effect reduction | G. D. SEARLE & CO. (US) | 1995-05-23 | — | — | US | disclosed |