Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 7/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973893 | 0.90 | POLB (0.38) | KIF11POLBPPARDPTGS2 | |
| SCHEMBL8974093 | 0.88 | CA2 (0.44) | CA2CA12CA1CA9PTGS1 | |
| SCHEMBL8974154 | 0.86 | KIF11 (0.40) | KIF11CA2CA12CA1MAPT | |
| SCHEMBL8974201 | 0.85 | KIF11 (0.57) | KIF11CA2CA12CA1MAPT | |
| SCHEMBL8974771 | 0.83 | KCNH2 (0.42) | KIF11CA2CA12CA1CA9 | |
| SCHEMBL8974144 | 0.83 | KIF11 (0.44) | KIF11CA2CA12CA1MAPT | |
| SCHEMBL8973842 | 0.83 | KIF11 (0.43) | KIF11CA2CA12CA1MAPT | |
| SCHEMBL8973763 | 0.82 | POLB (0.41) | KIF11CA2CA12CA1MAPT | |
| SCHEMBL8973885 | 0.81 | KIF11 (0.46) | KIF11CA2CA12CA1MAPT | |
| SCHEMBL8974295 | 0.80 | KIF11 (0.43) | KIF11CA2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576339-A | Pyridyl substituted cyclopentadienes for the treatment of inflamation | HUANG HORNG-CHIH (US) | 1996-11-19 | — | — | US | disclosed |
| WO-1995030656-A1 | SUBSTITUTED CYCLOPENTADIENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1995-11-16 | — | — | WO | disclosed |
| US-5418254-A | Side effect reduction | G. D. SEARLE & CO. (US) | 1995-05-23 | — | — | US | disclosed |