Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 7/20 | 0.44 |
| ▸ | CA1 | P00915 | 7/20 | 0.44 |
| ▸ | CA2 | P00918 | 7/20 | 0.44 |
| ▸ | CA9 | Q16790 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 4/20 | 0.40 |
| ▸ | CA7 | P43166 | 4/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973879 | 0.94 | KIF11 (0.45) | KIF11CHRNA7CA12CA1CA2 | |
| SCHEMBL8974421 | 0.92 | PTGS2 (0.43) | KIF11PTGS2PTGS1ADAMTS4 | |
| SCHEMBL8973781 | 0.88 | KIF11 (0.59) | KIF11CHRNA7CA12CA1CA2 | |
| SCHEMBL8974117 | 0.87 | PTGS2 (0.40) | PTGS2PTGS1 | |
| SCHEMBL8974407 | 0.86 | PTGS2 (0.41) | CA12CA1CA2CA9CA4 | |
| SCHEMBL8974327 | 0.85 | KIF11 (0.50) | KIF11CHRNA7CA12CA1CA2 | |
| SCHEMBL8974209 | 0.85 | KIF11 (0.52) | KIF11CHRNA7CA12CA1CA2 | |
| SCHEMBL8974757 | 0.84 | CA2 (0.41) | CA12CA1CA2CA9CA4 | |
| SCHEMBL8974073 | 0.83 | KIF11 (0.50) | KIF11CHRNA7CA12CA1CA2 | |
| SCHEMBL8973691 | 0.83 | CA1 (0.43) | KIF11CHRNA7CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576339-A | Pyridyl substituted cyclopentadienes for the treatment of inflamation | HUANG HORNG-CHIH (US) | 1996-11-19 | — | — | US | disclosed |
| US-5418254-A | Side effect reduction | G. D. SEARLE & CO. (US) | 1995-05-23 | — | — | US | disclosed |