SCHEMBL897525

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20004206	0.83	ALK (0.38)	ALKALDH1A1MAPK1GAA
	SCHEMBL20061137	0.81	S100B (0.38)	ALKMAPTALDH1A1PKMMAPK1
	SCHEMBL897012	0.81	HTR2A (0.45)	ALKHTR2AHTR2CHTR2BTSHR
	SCHEMBL20004650	0.81	ALK (0.38)	ALKALDH1A1MAPK1
	SCHEMBL897888	0.80	TAAR1 (0.39)	ALKHTR2AHTR2CHTR2BMAPT
	SCHEMBL897378	0.80	ALK (0.43)	ALKMAPTALDH1A1GAATSHR
	SCHEMBL20366497	0.79	ALK (0.36)	ALK
	SCHEMBL7805174	0.79	ALK (0.36)	ALK
	SCHEMBL20061173	0.78	S100B (0.38)	ALKMAPTALDH1A1PKMGAA
	SCHEMBL29940794	0.78	CHEK1 (0.38)	ALKHTR2AMAPTALDH1A1MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.