SCHEMBL897378

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL897635	0.82	ALDH1A1 (0.58)	MAPTALDH1A1GAATSHRNPBWR1
	SCHEMBL897511	0.81	MAPT (0.57)	ALKMAPTALDH1A1GAATSHR
	SCHEMBL897525	0.80	ALK (0.43)	ALKMAPTALDH1A1GAATSHR
	SCHEMBL20004206	0.78	ALK (0.38)	ALKALDH1A1GAAKMT2ASMN1; SMN2
	SCHEMBL20366497	0.77	ALK (0.36)	ALKKMT2A
	SCHEMBL20061137	0.77	S100B (0.38)	ALKMAPTALDH1A1GAATSHR
	SCHEMBL897012	0.77	HTR2A (0.45)	ALKTSHRKDM4E
	SCHEMBL20004650	0.76	ALK (0.38)	ALKALDH1A1KMT2A
	SCHEMBL897888	0.75	TAAR1 (0.39)	ALKMAPTALDH1A1TSHRKMT2A
	SCHEMBL31525223	0.74	TRPV4 (0.43)	TRPV4MAPTALDH1A1GAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.