SCHEMBL897012

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20004206	0.83	ALK (0.38)	ALK
	SCHEMBL20061137	0.81	S100B (0.38)	ALKTSHR
	SCHEMBL897525	0.81	ALK (0.43)	HTR2AHTR2CHTR2BALKTSHR
	SCHEMBL897888	0.80	TAAR1 (0.39)	HTR2AHTR2CHTR2BALKKDM4E
	SCHEMBL20061173	0.78	S100B (0.38)	ALKTSHR
	SCHEMBL29940534	0.78	ALK (0.38)	ALKKDM4ETSHR
	SCHEMBL897548	0.78	CA9 (0.43)	ALKKDM4E
	SCHEMBL7812922	0.78	ALK (0.43)	ALK
	SCHEMBL27087561	0.78	CHEK1 (0.38)	HTR2AALKKDM4EAR
	SCHEMBL27087621	0.78	ALK (0.38)	ALKKDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.