Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15234422 | 0.73 | ELANE (0.40) | MTNR1AMTNR1BMAPTALDH1A1L3MBTL1 | |
| SCHEMBL8975628 | 0.72 | TSHR (0.45) | MTNR1AMTNR1BMAPTALDH1A1L3MBTL1 | |
| SCHEMBL9654634 | 0.70 | MTNR1A (0.40) | MTNR1AMTNR1BMAPTALDH1A1L3MBTL1 | |
| SCHEMBL9421959 | 0.70 | LTA4H (0.50) | ALDH1A1L3MBTL1HSD17B10TSHRTDP1 | |
| SCHEMBL28100335 | 0.68 | MTNR1A (0.39) | MTNR1AMTNR1BMAPTALDH1A1L3MBTL1 | |
| SCHEMBL8975642 | 0.68 | MAPT (0.40) | MTNR1AMTNR1BMAPTALDH1A1L3MBTL1 | |
| SCHEMBL9330189 | 0.67 | MAPT (0.36) | MAPTALDH1A1TDP1GAA | |
| SCHEMBL237878 | 0.66 | CA4 (0.43) | TSHR | |
| SCHEMBL7391389 | 0.66 | LTA4H (0.41) | ALDH1A1L3MBTL1HSD17B10TSHRTDP1 | |
| SCHEMBL479411 | 0.66 | LTA4H (0.41) | MAPTALDH1A1HSD17B10TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543919-B1 | USE OF HETEROCYCLIC AMINO-ALCOHOL COMPOUNDS IN THE MANUFACTURE OF A MEDICAMENT FOR TREATMENT OF CNS DISEASES | SEARLE & CO (US) | 1996-04-10 | — | — | EP | claimed |