Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 3/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029428 | 0.71 | LTA4H (0.38) | LTA4HTP53CA4 | |
| SCHEMBL10534542 | 0.70 | CHRNB2 (0.39) | LTA4HTP53CA4ALDH1A1NPSR1 | |
| SCHEMBL9421959 | 0.70 | LTA4H (0.50) | LTA4HTDP1RECQLCA4ALDH1A1 | |
| SCHEMBL6572639 | 0.68 | LTA4H (0.42) | MAPTLTA4HTDP1TP53CA4 | |
| SCHEMBL8975377 | 0.67 | MTNR1A (0.42) | MAPTTDP1ALDH1A1GAA | |
| SCHEMBL237878 | 0.66 | CA4 (0.43) | HTR1BHTR1DLTA4HCA4 | |
| SCHEMBL1033246 | 0.66 | HTR1B (0.42) | MAPTALOX12HTR1BHTR1DLTA4H | |
| SCHEMBL4709806 | 0.66 | KCNH2 (0.44) | LTA4HHTR1ASLC6A3DRD2DRD3 | |
| SCHEMBL31544590 | 0.66 | KCNH2 (0.44) | LTA4HHTR1ASLC6A3DRD2DRD3 | |
| SCHEMBL7085752 | 0.65 | CA4 (0.48) | MAPTLTA4HTDP1KMT2ACA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328251-B1 | 2-(2-Hydroxy-3-phenoxypropylamino)ethylphenoxyacetamides and processes and intermediates for their preparation | ICI PLC (GB) | 1994-04-13 | — | — | EP | claimed |