Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975637 | 0.79 | SLC6A3 (0.56) | GAAKDM4ELMNACA1ALOX15 | |
| SCHEMBL6671288 | 0.76 | CTSD (0.70) | GAASMN1; SMN2LMNACTSDSTAT3 | |
| Hydrochloric Acid SCHEMBL31097029 | 0.74 | CTSD (0.68) | GAASMN1; SMN2LMNACTSDSTAT3 | |
| SCHEMBL9129759 | 0.74 | LIG1 (0.54) | LIG1GAASMN1; SMN2KDM4EMPO | |
| SCHEMBL8975646 | 0.74 | ABCB1 (0.46) | KDM4EHSD17B10NPC1RAB9AHCRTR1 | |
| SCHEMBL1331243 | 0.73 | GAA (0.73) | LIG1GAASMN1; SMN2KDM4EMPO | |
| SCHEMBL5302217 | 0.73 | KDM4E (0.65) | LIG1GAASMN1; SMN2KDM4EMPO | |
| SCHEMBL974852 | 0.73 | CTNNB1 (0.62) | LIG1GAASMN1; SMN2KDM4EHDAC8 | |
| SCHEMBL28010210 | 0.73 | KDM4E (0.65) | LIG1GAASMN1; SMN2KDM4EMPO | |
| SCHEMBL10780944 | 0.73 | LIG1 (0.53) | LIG1GAASMN1; SMN2KDM4EMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10562920-B2 | Ln(III) and Ga(III) metallacrown complexes | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2020-02-18 | — | — | US | disclosed |
| US-20180127438-A1 | LN(III) AND GA(III) METALLACROWN COMPLEXES | NATIONAL SCIENCE FOUNDATION | 2018-05-10 | — | — | US | disclosed |
| EP-3283497-A1 | LN(III) AND GA(III) METALLACROWN COMPLEXES | The Regents of The University of Michigan (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016166380-A1 | LN(III) AND GA(III) METALLACROWN COMPLEXES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127438-A1 | LN(III) AND GA(III) METALLACROWN COMPLEXES | NEU3, GALNT3, LGALS3 | LIG1 70/4885GAA 102/4885SMN1; SMN2 2890/4885 |
| US-10562920-B2 | Ln(III) and Ga(III) metallacrown complexes | NEU3, GALNT3, LGALS3 | LIG1 70/4885GAA 102/4885SMN1; SMN2 2890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.