Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16625723 | 0.80 | MEN1 (0.53) | FEN1EGFRSRCTNKSPDE10A | |
| SCHEMBL8976235 | 0.78 | FEN1 (0.42) | FEN1EGFRSRCTNKSPDE10A | |
| SCHEMBL280139 | 0.77 | GPR3 (0.58) | FEN1EGFRSRCPDE10AL3MBTL1 | |
| SCHEMBL16625727 | 0.76 | CCNB2 (0.42) | FEN1EGFRSRCPDE10AKDM4E | |
| SCHEMBL18381782 | 0.75 | GPR3 (0.56) | FEN1EGFRSRCPDE10AL3MBTL1 | |
| SCHEMBL17034477 | 0.75 | DDB1 (0.51) | FEN1EGFRSRCHCRTR1NPC1 | |
| SCHEMBL1609990 | 0.74 | FEN1 (0.56) | FEN1EGFRSRCTNKSL3MBTL1 | |
| SCHEMBL19267550 | 0.72 | EGFR (0.38) | FEN1EGFRSRCPDE10AMEN1 | |
| SCHEMBL8975983 | 0.72 | MAOA (0.43) | MEN1KMT2AL3MBTL1KDM4EMAPT | |
| SCHEMBL9968131 | 0.71 | RORA (0.39) | FEN1PDE10AMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532261-A | TREATING STAPHYLOCOCCUS INFECTIONS | MERCK & CO., INC. (US) | 1996-07-02 | — | — | US | disclosed |