SCHEMBL897653

SCHEMBL897653

O=Cc1cccc(C=Cc2ccccc2)c1C=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 5/20 0.48
TRPA1 O75762 3/20 0.48
LMNA P02545 2/20 0.46
MEN1 O00255 1/20 0.46
THRB P10828 1/20 0.46
BLM P54132 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ALDH1A1 P00352 2/20 0.44
CYP2A6 P11509 1/20 0.44
ALOX5 P09917 1/20 0.43
MAPK1 P28482 1/20 0.43
NR1H2 P55055 1/20 0.41
PPARG P37231 1/20 0.41
CHAT P28329 2/20 0.40
DPYD Q12882 1/20 0.40
MAOB P27338 2/20 0.39
CYP19A1 P11511 1/20 0.39
MAOA P21397 1/20 0.39
DHFR P00374 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28051597 0.92 NFE2L2 (0.48) NFE2L2TRPA1LMNAMEN1THRB
SCHEMBL26982578 0.86 ALDH1A1 (0.43) NFE2L2TRPA1LMNAMEN1THRB
SCHEMBL9294048 0.83 TRPA1 (0.63) NFE2L2TRPA1
SCHEMBL9294051 0.83 TRPA1 (0.63) NFE2L2TRPA1
SCHEMBL24385991 0.83 LMNA (0.62) NFE2L2TRPA1LMNAMEN1THRB
SCHEMBL192400 0.83 LMNA (0.62) NFE2L2TRPA1LMNAMEN1THRB
SCHEMBL30958792 0.83 LMNA (0.62) NFE2L2TRPA1LMNAMEN1THRB
SCHEMBL192399 0.83 LMNA (0.62) NFE2L2TRPA1LMNAMEN1THRB
SCHEMBL478036 0.81 NFE2L2 (0.58) NFE2L2TRPA1MEN1KMT2ANR1H2
SCHEMBL478037 0.81 NFE2L2 (0.58) NFE2L2TRPA1MEN1KMT2ANR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9164376-B2 Patterning nano-scale patterns on a film comprising unzipping copolymers GLOBALFOUNDRIES INC. (KY) 2015-10-20 US disclosed
US-8574815-B2 Patterning nano-scale patterns on a film comprising unzipping copolymers INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-11-05 US disclosed
US-8450043-B2 Patterning nano-scale patterns on a film comprising unzipping copolymers INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-05-28 US disclosed
US-20120297905-A1 PATTERNING NANO-SCALE PATTERNS ON A FILM COMPRISING UNZIPPING COPOLYMERS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-11-29 US disclosed
US-20120301672-A1 PATTERNING NANO-SCALE PATTERNS ON A FILM COMPRISING UNZIPPING COPOLYMERS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-11-29 US disclosed
US-20120082944-A1 Patterning nano-scale patterns on a film comprising unzipping copolymers INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-04-05 US disclosed
EP-0229592-B1 PROCESS FOR THE PREPARATION OF STILBENE-4,4'-DIALDEHYDES CIBA-GEIGY AG (CH) 1989-10-18 EP disclosed
US-4778928-A REDUCTION OF 4,4'-STILBENEDINITRILE WITH AN ALUMINUM HYDRIDE CIBA-GEIGY CORPORATION (US) 1988-10-18 US disclosed
EP-0229592-A1 Process for the preparation of stilbene-4,4'-dialdehydes CIBA-GEIGY AG (CH) 1987-07-22 EP disclosed